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GATA2 Development

By leonards221
  • Period: to

    GATA2 Development

    The "Master Regulator"
  • GATA2 Discovered

    GATA2 Discovered

    Dr. Bresnick and his team discovers GATA2 and "hot spots," called GATA switch sites where GATA1 and GATA2 undergo special activity.
  • "Research indicates that downstream genes are impacted when the switch site is altered, leading to abnormal development of the adult blood system." - Dr. Emery Bresnick

    "Research indicates that downstream genes are impacted when the switch site is altered, leading to abnormal development of the adult blood system." - Dr. Emery Bresnick

  • scientists were testing +9.5 GATA2 in mice and knocked out the switch site, which caused the embryos to die within 14 days.

    scientists were testing +9.5 GATA2 in mice and knocked out the switch site, which caused the embryos to die within 14 days.

  • The study appeared on the Journal of Clinical Investigation.

    The study appeared on the Journal of Clinical Investigation.

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