-
-
-
Endoderm, Mesoderm, and Intraembryonic Coelom take place
Lung buds sprout as a growth from the ventral wall of the foregut, also where lobar division takes place -
Tubular branching continues, all segmental bronchi become present, stage is critical for formation of conducting airways
epithelial tubes surrounded by mesenchyme are formed -
bronchioles produced, capillaries in contact with cuboidal epithelium increase, alveolar epithelium begins to develop, future gas exchange regions can be identified
-
-
air sacs and alveolar ducts become developed, vascular tree grows, gas exchange region expands, fibroblastic cells produce extracellular matrix, collagen and elastin, saccules form
-
-
number and size of capillaries and alveoli increase, amniotic fluid and respiratory motions aid in lung maturation, microvascular maturation occurs
-
-
Lung and Respiratory System fully developed