Events Leading to RCT Globalization

  • Period: to

    Tuskegee Syphilis Study

    Participants- 400/200
    Goal- Observe progression, contraction of syphilis
    No treatment provided (Shah 2006)
  • Originiation of Randomized Clinical Trial

  • Nuremburg Code

  • Salk Polio Vaccine

  • Period: to

    Growing distrust

  • Tuskegee Expose

  • WMA Belmont Report

    WMA Belmont Report
    ETHICAL PRINCIPLES for MED. RESEARCH INVOLVING HUMAN SUBJECTS
    -Respect for Autonomy
    -Nonmaleficence
    -Beneficence
    -Justice (Beaucamp & Childress)