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In 1 BC When Lycaon the king of Arcadia in ancient Greece offended the gods by offering human flesh and was punished by becoming a werewolf. This Story is also related in "The Metamorphoses" written by Ovid.
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In the early 16th century in regions of Prussia, Livonia, and Lithuania, fierce massacres by large, upright bear-like animals began to be reported.
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France in the sixteenth century suffered thousands of murders by beasts that looked like humanoid wolves, so the few witnesses said.
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In the 17th century England persecuted people accused of witchcraft, as attacks by wolf-like beasts occasionally occurred, which were believed to be the work of witchcraft.
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From the Middle Ages the legend of the werewolf seems to spread throughout Europe due to cases around the continent, keeping the suspense at the time
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In the south of France, in the period from 1764 to 1767 there was a creature that terrorized the province of Gévaudan; The beast was frequently described as a giant wolf, attacking livestock and humans without distinction. Accounts say that he was struck down by a silver bullet. Hence the idea that silver damages them.
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Currently some modern researchers have tried to use conditions such as rabies, hypertrichosis as an explanation for the werewolf belief, although they are not entirely similar.