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Began researching inheritance. Mendel recognised a pattern of inheritance in offspring from parents, this lead him to being able to predict ratios and formulate principle of inheritance which became known as Mendel’s Laws. Known as ‘the Father of Genetics’
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1969 was when most of his work occurred, he isolated the nuclein, determining chemicals it was made of
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Discovered that chromosomes are heredity and that they are distinctively separate entities. Sutton also established that the separation of chromosomes directly related to Mendel’s Laws of inheritance.
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Observed that chromosomes were not identical, they were haploid meaning sex cells (gametes) have half the number of chromosomes of normal body cells which are diploid.
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Spent a large amount of time studying nucleic acids, publishing many different papers but he is mostly remembered by his incorrect tetranucleotide theory of DNA
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Studied the behaviour of chromosomes for 17 years. Continuing to develop ideas and proof about the chromosomal theory, as well as genetic linkage, disjunction and crossing over.
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Presented crucial facts and evidence that lead to the discovery of the DNA’s molecular structure, as well as discovering the (G+C):(T+A) ratio
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Presented DNA findings through X-ray crystallography at a conference inspiring Watson’s study of DNA.
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Collaborated with Crick building a 3-D model of DNA to discover how it works and its structure
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Collaborated with Watson building a 3-D model of DNA to discover how it works and its structure
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Used X-ray diffraction to determine and seperate the two different kinds of ‘hydration forms’ of DNA, this allowed accurate measurements to be taken.
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By using Watson and Crick’s method of model building, Linus was able to propose that the DNA structure had a triple-standard helix.