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Surgeon-General to the Royal Artillery treated a patient that had diabetes with a dietary restriction.
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He discovered that the liver stored glycogen and secreted a sugary substance into the blood. He then assumed that it cased diabetes. But at this time they thought the nervous system controlled all organs.
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He said Bernard’s liver theory was found incorrect. von mering said that when you removed the pancreas it caused people to have diabetes. Von and his partner Minkowski worked on extracting an antidiabetic substance from the pancreas but could not find a way to do this.
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In Canada by Fredrick Banting, who read about the association between the pancreas and diabetes became convinced that he could find the antidiabetic substance.
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A 14-year-old boy became the first human patient to receive insulin made by Banting and Best.
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Those injections failed and another purified form was injected.
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They needed insulin that would last longer and they figured out that insulin can cause pain and abscesses. The protamine zinc insulin was introduced.
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then the Lente insulins were introduced and they were more effective.
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The scientific investigation of diabetes was improved by the technique of immunoassay by Solomon Berson and Rosalind Yalow