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Colonial period
- A Dutch ship brings about twenty black Africans to the Colony of Virginia as indentured servants. (1619)
- About 2,000 of the 40,000 inhabitants of colonial Virginia are imported slaves. (1671)
- Non-slaveholding farmers in Virginia think slave labor threatens their livelihoods. (1719)
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American Revolution and Confederation period
- The United States Declaration of Independence declares "that all men are created equal, that they are endowed by their Creator with certain unalienable Rights. (1776)
- Massachusetts bans slavery in its constitution. (1780)
- July 13: The Continental Congress under the Articles of Confederation passes the Northwest Ordinance to govern territory north of the Ohio River and west of Pennsylvania.
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Early period under the Constitution
- August 7: Congress re-adopts the Northwest Ordinance under the Constitution.
- Vermont admitted as a free state
- The United States purchases the Louisiana Territory from France.
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War of 1812
- Louisiana is admitted as a slave state
- Mississippi, a slave state, is admitted the union
- U.S. slave population in the 1820 United States Census: 1,538,000
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The Compromise Tariff of 1833
- Nullification crisis by lowering some rates.
- The abolitionist American Anti-Slavery Society is founded in Philadelphia.
- Abolitionist Lydia Maria Child of Massachusetts publishes An Appeal in Favor of That Class of Americans Called Africans.
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Compromise of 1850 through 1860 election
- April 17: U.S. Senator Henry S. Foote of Mississippi pulls a pistol on an anti-slavery Senator on the floor of the U.S. Senate
- Henry Clay proposes the Compromise of 1850 to handle California's petition for admission to the union as a free state and Texas's demand for land in New Mexico.
- Utah is organized as a territory and adopts a slave code.
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Knights of the Golden Circle,
- Former Mississippi Governor John A. Quitman begins to raise money and volunteers to invade Cuba
- he Know-Nothing Party or American Party, which includes many nativist former Whigs
- George Fitzhugh's pro-slavery Sociology for the South is published
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1860 election
- Abraham Lincoln wins the 1860 presidential election
- Charleston, South Carolina authorities arrest a Federal officer
- The Provisional Confederate Congress chosen by the Montgomery convention approves a Peace Commission to the United States
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Aftermath 1861
- Kentucky and North Carolina immediately refuse to provide troops in response to Lincoln's call
- Federal troops are only partially successful in destroying the armory and arsenal at Harpers Ferry, Virginia,
- President Lincoln declares a blockade of the Confederate States
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Licolns Blockade
- Federal forces abandon and attempt to destroy the Gosport Navy Yard
- The 7th New York Volunteer Infantry Regiment arrives in Washington, D.C.
- Governor Beriah Magoffin of Kentucky declares Kentucky to be neutral and forbids both movement of troops