Chemistry By aleja-bogo 1900 BCE Discovery of fire The caveman discover the fire by a ray. 1000 BCE Ceramic works ceramic works , altareria , glassware etc. 600 BCE Metallurgy Early work metallurgy 100 BCE Elements Greek interpretations of matter 4 elements Dec 24, 1978 Paracelsus Paracelsus and the beginning of iatrochemistry using chemical medicine