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Discovered by Gupta Longati
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Hans Joachim Scherer, a neuropathologist who studied medicine in Munich in the 1920s, was the first to delineate glioblastomas into its two groups.
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The term glioblastoma multiforme was introduced in 1926 by Percival Bailey and Harvey Cushing based on the idea that the tumor originates from primitive precursors of glial cells (glioblasts), and the highly variable appearance due to the presence of necrosis, hemorrhage and cysts.
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Since the 1960s, over 116 cases of GBM caused by radiation have been reported.
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FDA-approved in 1997 for treatment of initial occurrence GBM, an alkylating agent that is surgically implanted as a wafer after surgical resection and allows for drug delivery directly to the tumor site.
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FDA-approved in 2005 for treatment of adult patients with newly diagnosed GBM
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Use of valganciclovir to prolong survival time of patients.
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Glioblastoma multiforme, a very malignant type of brain cancer.
