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In January 2008, child clinical psychologist Geraldine Dawson, PhD., became Autism Speaks' chief science officer.
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From February 2009 until 2020, Autism Speaks has used the "Wubbzy" character from Wow! Wow! Wubbzy! as a mascot.
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In April 2010, the organization named Yoko Ono its first "Global Autism Ambassador."
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On May 1, 2015, Bob Wright resigned as chairman of the organization. He was succeeded by Brian Kelly who had served as Chair of the Audit and Family Services Committees for the organization, and is co-founder of Eastern Real Estate LLC.
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Suzanne and Bob Wright formed this organization because they had a grandson with autism.