Aspirin

Brugnatelli and Fontana, had in fact already obtained salicin in 1826, but in a highly impure form

Aug 23, 1826

a professor of pharmacy at the University of Munich, isolated a tiny amount of bitter tasting yellow, needle-like crystals, which he called salicin.

Jun 15, 1828

Johann Buchner, professor of pharmacy at the University of Munich, isolated a tiny amount of bitter tasting yellow, needle-like crystals, which he called salicin. Two Italians, Brugnatelli and Fontana, had in fact already obtained salicin in 1826, but in a highly impure form

scientists discovered that it was the compound called salicin in willow plants which gave you the pain relief.

Jul 27, 1829

Henri Leroux had improved the extraction procedure to obtain about 30g from 1.5kg of bark

Dec 2, 1829

Raffaele Piria [an Italian chemist] then working at the Sorbonne in Paris, split salicin into a sugar and an aromatic component

May 21, 1838

, Raffaele Piria [an Italian chemist] then working at the Sorbonne in Paris, split salicin into a sugar and an aromatic component (salicylaldehyde) and converted the latter, by hydrolysis and oxidation, to an acid of crystallised colourless needles, which he named salicylic acid."