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British chemist Davy Humphry was the first to suggest nitrous oxide as an anesthetic.
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Henry Hill Hickman experimented with nitrous oxide as an anesthetic.
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Crawford Long was the first to use ether as an oral inhalable anesthetic.
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Horace Wells first used nitrous oxide during dental operation.
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Crawford Long used ether during child births to relieve pain.
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W.T.G. Morton later used ether in more serious operations and developed its effectiveness.
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James Simpson used chloroform to ease pain during the delivery of newborns.
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The use of epidural anestesia had begun, but was not yet accepted in clinical practice.
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The use of epidural anesthesia was inducted into clinical practice.
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Medical schools began offering formal training in anesthesia.
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The study and administration of anesthesia became its own study called anesthesiology.
