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Valverdi used freezing mixtures of snow and ice for surgical anesthesia.
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Christopher Wren first experimented with an I.V.
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Johann Elsholtz- first attempted I.V. anesthesia
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Johann Joachim Becher- discovered Ethylene
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W.G. Frobenius- "Sweet vitriol", first synthesized in 1540, was named Ether
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Joseph Priestly- discovered nitrous oxide
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Humphrey Davey- called nitrous oxide "laughing gas"
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Richard Pearson- used Ether as an inhaled anesthetic
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Friedrich Serturner- extracted morphine from opium
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Latta- introduction of intravenous infusion of saline solutions to patents in shock
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Discovery of chloroform
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Removal of a tooth by doctor Pope under the influence of ether
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Crawford Long- performed the painless removal of a tumor from the neck of a patient under the influence of ether
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Amputation of a leg under nitrous oxide
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Horace Wells- removes wisdom teeth while demonstrating nitrous oxide; again, in 1846, he removed a tooth from a medical student who claimed to feel pain, though less than expected
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William Morton- first public demonstration of ether at Massachusetts General Hospital
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James Simpson- Introduction of ether in childbirth; later, he used chloroform in surgeries
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John Snow administered chloroform to Queen Victoria at the birth of Prince Leopold
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Alfred Einhorn- discoverey of procain (Novacain)
