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Surgeon General John Rollo treats diabetic patient by dietary restriction.
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Claude Bernard discovered that the liver stored glycogen and secreted a sugary substance into the blood; he assumed the substance caused diabetes.
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Von Mering disproved Bernard's liver theory when he discovered that removal of the pancreas caused diabetes.
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the discovery of insulin took place in Canada by Frederick Banting; he performed an experiment where is extracted pancreas from a healthy dog and injected it into a dog with diabetes and not into another with diabetes.
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the first human, a 14 year old boy, recieved Banting's and Charles Best's insulin which led to the injections being purified a week later.
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insulin is produced commercially as a fast acting soluble, leading to multiple injections being necessary for continued results. Also led to people developing a longer lasting insulin.
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insulin is crystallized by JJ Abel
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the investigation of diabetes improves with the immunoassay by Solomon Berson and Rosalind Yalow - concentrations can be consistently measured
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the first testng for recombinant DNA insulin is announced.
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first biosynthetic human insulin is introduced
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inhalable insulin is produced and given out to consumers.
