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Plants, animals, diseases, people, and ideas have been introduced from Europe, Asia, and Africa to America and vice versa.
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After sailing across the Atlantic Ocean, Columbus stumbled upon land he thought was Asia.
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John Cabot discovered Newfoundland and Cape Breton Island on the North American coast.
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His initial voyage to India by way of Cape of Good Hope was the first to link Europe and Asia by an ocean route, connecting the Atlantic and the Indian oceans
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He found the mouth of the Amazon River, as well as several other rivers.
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Balboa climbed a mountain peak and sighted the Pacific Ocean, which the Spaniards called the Mar del Sur (South Sea)
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The Aztecs, under their last ruler, Cuauhtémoc, resisted fiercely but were finally defeated in late 1521. Cortés razed Tenochtitlan, building his own capital over its ruins, and proclaimed the Aztec Empire to be New Spain.
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The Philippines were claimed in the name of Spain in 1521 by Ferdinand Magellan
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The Spanish conquest of the Inca Empire, also known as the Conquest of Peru, was one of the most important campaigns in the Spanish colonization of the Americas
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Coronado explored parts of what becomes parts of the Southwest United States.
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Juan Rodriguez Cabrillo and his crew entered San Diego Bay who were the first Europeans to visit California.
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Triangular Trade across the Atlantic was a series of trade routes that linked Europe, Africa, and the Americas.
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The settlement became the first permanent English settlement in North America
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Hudson secured backing from the British East India Company to resume his search for a passage to Asia
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Plymouth Colony was the first permanent English colony in New England from 1620 and the third permanent English colony in America
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the Pilgrims, or English Protestants who rejected the Church of England, landed in Plymouth, Massachusetts