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Coordinated attacks involving hijacked airliners kill 2,976 people from 90 countries. An FBI investigation links the hijackers to the terrorist organization al Qaeda.
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In an address to a joint session of Congress, President George W. Bush issues a list of demands -- including a call to turn in al Qaeda's leaders -- to Afghanistan's Taliban regime. "The leadership of al Qaeda has great influence in Afghanistan and supports the Taliban regime in controlling most of that country. In Afghanistan we see al Qaeda's vision for the world," Bush says.
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Military action in Afghanistan, known as "Operation Enduring Freedom," begins as 15 land-based bombers strike military targets and al Qaeda training camps inside Afghanistan.
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Army Sgt. 1st Class Daniel H. Petithory, 32, of Cheshire, died Dec. 5, 2001 in a friendly fire bombing in Afghanistan.
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"American and coalition forces are in the early stages of military operations to disarm Iraq, to free its people and to defend the world from grave danger," President Bush says in a televised address.
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Marine Staff Sgt. Phillip A. Jordan, 42, of Enfield, Conn., died March 23, 2003 near Nasiriyah, Iraq.
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In a speech delivered aboard the USS Abraham Lincoln, President Bush declares that major combat operations in Iraq have ended, and that "..now our coalition is engaged in securing and reconstructing that country."
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Sgt. Gregory Belanger, 24, of Deerfield, died Aug. 27, 2003 when a bomb struck his vehicle in Hallia, Iraq.
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Army Spc. Jeremy F. Regnier, 22, of Littleton, N.H., a native of Agawam, died Oct. 10, 2003 in a bomb explosion in Baghdad, Iraq.
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Army Pfc. Jeffrey F. Braun, 19, of Stafford, Conn., died Dec. 12, 2003 from a non-hostile gunshot wound in Baghdad, Iraq.
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Army Sgt. Glenn R. Allison, 24, of Pittsfield, died Dec. 18, 2003 during physical training in Baghdad, Iraq.
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Army Chief Warrant Officer 2 Stephen M. Wells, 29, of North Egremont, died Feb. 25, 2004 in a helicopter crash in Habbinayah, Iraq.
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Army Pfc. Markus J. Johnson, 20, of Springfield, died June 1, 2004 when a vehicle rolled over in Anbar Province, Iraq.
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Marine 1st Lt. Travis J. Fuller, 26, of Granville, died Jan. 25, 2005 in a helicopter crash.
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Marine Capt. John W. Maloney, 36, of Chicopee, died June 15, 2005 when his vehicle struck a roadside bomb in Ramadi, Iraq.
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Army Lt. Col. Leon G. James II, 46, a Springfield native, died Oct. 10, 2005 in a bomb blast outside Baghdad, Iraq.
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Marine Cpl. Stephen R. Bixler, 20, of Suffield, Conn., died May 4, 2006 while on foot patrol in Iraq.
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Army Spc. David J. Babineau, 25, of Springfield, died June 16, 2006 in an attack south of Baghdad, Iraq.
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Staff Sgt. Clint J. Storey, 30, of Enid, Okla., whose widow is from Palmer, died Aug. 4, 2006 in a bomb explosion in Ramadi, Iraq.
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Marine Lance Cpl. Philip A. Johnson, 19, of Enfield, Conn., died Sept. 3, 2006 in a roadside attack west of Baghdad, Iraq.
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Marine 2nd Lt. Joshua L. Booth, 23, of Sturbridge, died Oct. 17, 2006, in battle in Haditha, Iraq.
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Army Spc. Christopher M. Wilson, 24, formerly of Chicopee, died March 29, 2007 of injuries suffered in a grenade explosion at Korengal Outpost, Afghanistan.
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Army Staff Sgt. Daniel A. Newsome, 27, was killed by a roadside bomb on June 27, 2007, in Baghdad, Iraq.
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Army Cpl. Jeremy P. Bouffard, 21, of Middlefield, died Aug. 22, 2007 in a helicopter crash in Iraq.
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Army Spc. Ari D. Brown-Weeks, 23, of Leyden died Sept. 10, 2007 in a truck accident in Iraq.
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Army Spc. Kenneth J. Iwasinski, 22, of Belchertown, died Oct. 14, 2007 following a roadside bomb explosion in Baghdad, Iraq.
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A roadside bomb kills four soldiers in southern Baghdad, bringing the total number of U.S. soldiers killed in Iraq to 4,000. [Reuters: Four U.S. soldiers killed in Iraq, death toll 4,000]
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Army Sgt. 1st Class Kevin A. Dupont, 52, of Chicopee, died June 17, 2009, of injuries suffered when his vehicle ran over an improvised explosive device in Afghanistan March 8.
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President Obama announces the commitment of an additional 30,000 U.S. troops to Afghanistan, to be deployed in early 2010. [Full text of the address.]
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Marine Sgt. Joshua D. Desforges, 23, of Ludlow, died May 12, 2010, in the Helmand province of Afghanistan.
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NATO reports the death of a U.S. service member in a roadside bombing in southern Afghanistan. [NPR: 1,000th U.S. Military Death In Afghanistan]