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!st British East India company voyage departs from London, lead by John Lancaster.
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1st Dutch settlers arrive (from NJ), to colonize Manhattan Island.
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First American Indian (Powhatan) massacre of Europeans in Jamestown Virginia, 347 killed.
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Battle of Liaoluo Bay: Dutch East India Company defeated by Chinese Ming naval forces in southern Fujian sea.
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Battle of Naseby, Leicestershire: "New Model Army" under Oliver Cromwell & Thomas Fairfax beat royalists forces of English King Charles I.
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Dutch West Indies Co denies Peter Stuyvesant's desire to exclude Jews from New Amsterdam.
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1st fully documented human blood transfusion is performed by French physician, Dr. Jean-Baptiste Denys, when a small amount of sheep blood is transfused into a 15-year old boy, who survives the procedure.
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Roman Catholics banned from English parliament.
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The first confirmed tornado in America kills a servant at Cambridge, Massachusetts.
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Sarah Goode, Sarah Osborne, & Tituba arrested for witchcraft in Salem, Massachussets.