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The Black Death started in 1320. At first it affected the Middle East and China until 1346.
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The Black Death spread from a disease rats had then a flea would bite the rat. So then the flea bites the human which leads to the human getting the disease.
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The Black Death enters France through the port of Marseilles; northern Italy gets hit.
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The Black Death disapears from Europe, then comes back twelve years later to strike again.