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Elliott P. Joslin was the first to use insulin as a treatment for diabetes.
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John Rollo decided that diabetes should be treated by restricting a patient's diet.
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In the early 1800s, Claude Bernard discovered that the liver stores glycagon and secretes a sugary substance into the blood.
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Bernard's findings about the liver was proven wrong by Von Mering.
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Canadian surgeon Frederick Banting visited the University of Toronto to speak to the newly appointed head of the department of physiology, John J.R. Macleod, who had studied glucose metabolism and diabetes.
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Fredrick Banting, from Canada, discovered insulin.
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The first dose of insulin was given to a human, which failed.
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The first purified injections of insulin were given by Collip.
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Insulin is produced commercially, and advertised, and used to treat diabetes in most western countries.
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JJ Abel crystallized insulin for use.
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Longer acting, protamine zinc insulin was invented.
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Lente insulin was created.
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Fredrick Sanger won a Nobel Prize for discovering the composition of insulin.
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Soloman Berson and Rosalind Yalow improved the investigation of diabetes through a technique known as immunoassay.
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Insulin was first made chemically synthesized.
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Dorothy Hodgin discovered the 3-D structure of insulin.
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The FDA approved a modified human insulin (Humalog).
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Lantus (recombinant insulin glargine) was introduced by Sanofi Aventis US as the first analog basal insulin.
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Pramlintide, brand name Symlin, was approved in the U.S. as an injectable adjunct treatment for people who use insulin at mealtimes but still fail to achieve desirable blood glucose levels.
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FDA approved Invokana (Canagliflozin), the first in a new class of drugs known as the SGLT-2 inhibitors, for lowering elevated blood sugar in patients with type 2 diabetes.
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The USPSTF issued a final recommendation advising all pregnant women be screened for gestational diabetes after 24 weeks of pregnancy.
