-
The sweet smell of the urine of people with diabetes was noted by Thomas Willis
-
John Rollo, a surgeon general, treated a person with dietary restrictions. These restrictions include a diet low in sugar and glucose.
-
Claude Bernard discovered that the liver stored glucagon and secreted a sugary substance into the blood
-
A german scientist by the named of Von Mering, disproved Bernards liver theory when he removed the pancreas and realized that this resulted in diabetes, he tried to extract this antidiatic substance but failed.
-
Treatments included the use of dialy alkaline-sponge baths, and creosote(or clear opium) which is used to depress the central nervous system
-
Insulin discovered by Fredrick Banting and Charles Best after experiment with dog in which one dog was injected with substance from pancreas and one was not. The one that was not died a few weeks later.
-
A 14 year old boy was the first human to be injected with insulin. Although this is true, this attempt failed.
-
Because of the effectiveness of insuling Elli Lily was assigned to try to duplicate it, and at the end of 1923 insulin was being produced commerically and used to treat diabetes in many western countries.
-
Insulin crystalized by J.J Abel, so that insulin can be mass produced
-
Promanine zinc insulin introduced as a longer acting type of insulin
-
Lente insulin was introduced
-
Berson and Yallow discovered the immunoassay, which allowed minute to minute concentration readings of insulin. This technique is used in insulin pens and external insulin pumps.
-
Dorothy Hodgins discovered the 3-dimensional structure of insulin, which helpfigure out the biochemistry of how it would react in the body
-
There is trails that are being run for the creation of an artifical pancreas. The goal of this device is to have a single device that detects blood/glucose levels and regulates blood sugar without human interaction.
