Stem Cell Developments Throughout History

The term 'stem cell' is coined by Maximow

1908

https://youtu.be/evH0I7Coc54

Transfer of bone marrow into lethally irradiated mice shows that marrow, like spleen, is regenerative

1951

Mice with leukemia treated successfully with lethal radiation followed by bone marrow transplant

1956

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2405927/

First report of successful bone marrow transplants performed in human patients

Sep 12, 1957

First successful allogeneic marrow transplant reported in patient with leukemia; distinctive and powerfully regenerative cell resident in bone marrow, known from now on as stem cells

1965

https://youtu.be/GIy2nMnuGGI

Cetus Corporation, the first biotechnology was founded

1971

First successful bone marrow transplant from unrelated donor

1973

Stem cells used as vectors to deliver the genes needed to correct the genetic disorder SCID

1992

https://bethematch.org/patients-and-families/about-transplant/diseases-treated-by-transplant/severe-combined-immunodeficiency--scid-/

Patients with damaged corneas successfully treated with corneal stem cells

1994

International Society for Stem Cell Research (ISCF) established

Mar 30, 2001

US places restrictions on embryonic stem cell research

Aug 9, 2001

First successful cloning of human embryo to make stem cells

Jan 12, 2006

https://www.npr.org/sections/health-shots/2013/05/15/183916891/scientists-clone-human-embryos-to-make-stem-cells

Scientists created stem cells for 10 disorders

Sep 5, 2008

https://www.lifecell.in/stem-cell-banking/diseases-cured-by-stem-cells

Stem cell transplant reported to be promising treatment for curing HIV

Feb 11, 2009

U.S. President Barack Obama reversed restrictions on stem cell research imposed by former President George W. Bush

Mar 9, 2009

Stem cells taken from nose demonstrated to repair spinal cord injury

Oct 13, 2014

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678281/

Stem cells reported to provide substantial recovery in patients disabled by stroke

Jun 2, 2016

Small-scale case study showed power of stem cells to repair damaged scar tissue caused by heart attacks

Jul 24, 2016

https://youtu.be/C0dmOPDLKhY

Data published from 25 centres in 13 countries for 281 patients indicated autologous hematopoietic stem cell transplantation can halt the progression of MS disability

Feb 20, 2017

Gene therapy reported to successfully reverse sickle cell disease in first patient

Mar 2, 2017

https://sicklecellanemianews.com/stem-cell-transplant-sickle-cell-disease/

Researchers at University of Washington-Madison demonstrated the possibility of growing skin, bone marrow and blood vessels using plant scaffolds with stem cells

Mar 4, 2017

Gene therapy shown in clinical trials to halt progression of adrenoleukodystrophy, a fatal brain disease inherited by boys

Oct 4, 2017

Mouse and human cells reprogrammed into immune cells to fight cancer

Dec 7, 2018

https://cancercommun.biomedcentral.com/articles/10.1186/s40880-019-0393-5

Gene therapy shown to be promising in treating infants born with X-linked severe combined immunodeficiency (SCID-X1)

Apr 19, 2019