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The Soviet spacecraft Sputnik 2 was launched with a dog named Laika on board. Laika did not survive the voyage.
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The Soviet craft Sputnik 5 was launched, carrying the dogs Strelka and Belka. They became the first living beings to survive a trip into space.
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Russian cosmonaut Yuri Gagarin became the first human in space.
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Astronaut Alan Shepard became the first American in space
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Astronaut John Glenn became the first American in orbit.
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Valentina Nikolayeva Tereshkova became the first woman in space.
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The spacecraft Mariner 4 transmitted the first pictures of Mars.
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The Soviet spacecraft Zond 5 was launched and later became the first spacecraft to orbit the moon and return to Earth.
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Neil Armstrong and "Buzz" Aldrin became the first men on the moon.
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The Soviet Venera 7 became the first probe to land on Venus.
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The moon rover was driven on the moon for the first time.
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The U.S. launched its first space station, Skylab.
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Launch of the first of two spacecraft called Pioneer Venus, which would study the Venusian atmosphere.
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Aboard the space shuttle Columbia, Robert L. Crippen and John W. Young make the first mission in NASA's space shuttle program.
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--Sally Ride becomes first American woman in space with launch of shuttle mission STS-7 aboard the space shuttle Challenger.
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Guion S. Bluford, Jr., becomes first black man in space with launch of shuttle mission STS-8 aboard the space shuttle Challenger
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First major catastrophe for NASA, when space shuttle Challenger (mission STS-51L) explodes 73 seconds after takeoff with seven crewmembers aboard
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Pathfinder lands on Mars. The rover Sojourner would go on to explore the Martian surface for more than 80 days
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First piece of the International Space Station is launched.
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--Launch of Genesis, which would collect samples of atoms from solar wind. Genesis would be the first attempt to return samples to Earth since the Apollo moon mission in 1972.
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Crew of seven astronauts, including the first Israeli astronaut, is lost after a 16-day mission when the Columbia space shuttle explodes on re-entry. The accident was later attributed to damage sustained to foam insulation and has led NASA to understand how to safely repair similar damage on later missions.
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Mars Exploration Rovers Spirit and Opportunity launch.
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SpaceShipOne becomes the first privately built craft to reach outer space.