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Leonie was born September 16, 1844, in Sezanne, France.
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On October 11, 1871, she professed first vows in the new congregation she co-founded with Father Brisson called the Oblate Sisters of Saint Francis de Sales.
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Sister Leonie Aviat opened missions in South Africa and Ecuador.
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She died on January 10, 1914, six years after the death of Father Brisson.