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An interesting retrospective study found the likely first recorded case of PAM occurred in Ireland in 1909
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Subsequent investigations in Virginia using archived autopsy tissue samples identified PAM infections that may have occurred in Virginia as early as 1937
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The first confirmed PAM infections were reported in 1965 in Australia.
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In 1966, Fowler termed the infection resulting from N. fowleri primary amoebic Meningoencephalitis (PAM).
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Of all the 128 cases of PAM reported from the United States, the first patient that survived was from California in 1978
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In 1979, a girl swimming in the restored Roman bath in the English city of Bath swallowed some of the source water, and died five days later from Amebic Meningoencephalitis. Tests showed that N. fowleri was in the water
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Between 2001 and 2010, there were only 32 reported cases of people getting Naegleria fowleri in the United States, according to the Centers for Disease Control and Prevention. Most of the cases have been in the Southeast.
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The picture represents the number of reported PAM cases in the U.S. up to 2012
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After two cases of a deadly brain infection were linked to neti pots, government health officials have issued new warnings about using them safely.
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In 2013, a girl in Arkansas became the third known person in the last 50 years to survive the parasite after her doctors gave her an experimental drug, Miltefosine
