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Worked together to invent the compound microscope
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Made the first discovery of the cell
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Disproved the theory of spontaneous generation
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First to observe bacteria and protozoa
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Discovered the nucleolus in the nucleus of cells
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Discovered the nucleus in eukaryotic cells
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Contributed to the cell theory declaring that the cell is the basic building block of all plant matter
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Contributed to the cell theory concluding that all organisms are made of one or more cells
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Contributed to the cell theory, stating that every cell arises from another cell
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Developed the technique of gram staining
