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He contributed by producing the first compound microscope
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He looked at cork under a microscope and disovered cells.
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He looked at dental scrapings and discovered little things that look like animals on the scraping and callled them "animalcules" which are now bacteria in modern day.
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He found out that all plants are made up of cells.
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He found out that all animals are made of cells.
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He discovered that all cels are from preexisting cells.