-
He was born in Ghent, Flanders, on February 24.
He is baptized on March 7 in the Cathedral of Saint Bavo. -
His parents Felipe and Juana leave for Spain, staying in the care of Margarita de York.
-
Felipe and Juana set out again for Spain to claim the crown of Castile after the death of Isabel la Católica. That same year, Felipe died prematurely and Juana, considered a madwoman, was locked up in a convent in Tordesillas by her father Fernando.
-
Carlos's coming of age is declared, being named Lord of the Netherlands, ending the regency of Margarita.
-
On January 22 he is appointed by his grandfather, Fernando II of Aragon, governor and administrator of the Kingdoms of Castilla y León, on behalf of Juana I and the Crown of Aragon.
On January 23, King Ferdinand II dies.
On March 21, Carlos sent a letter to the Council of Castile informing him of his decision to appoint himself King.
In April, Cardinal Cisneros communicates the royal title by Castile. -
The Cortes of Castile swears Carlos as king along with his mother Juana.
-
On April 16, he was sworn in in the Cortes of Aragon with Juana.
On June 28, Carlos is elected King of Romans, becoming sovereign of the Holy Roman Empire. -
In Aragon the conflict of the Germanías takes place.
-
In Castile, the War of the Communities of Castile occurs.
-
First war against Francis I of France.
-
Hernán Cortés conquers the Mexica Empire, giving rise to the Kingdom of New Spain.
-
Juan Sebastián Elcano goes around the world for the first time and Spanish sovereignty over the archipelagos of the Philippines and the Marianas begins.
-
Second war against Francis I of France.
-
He marries Isabel of Portugal.
-
His son Felipe is born.
-
His daughter María is born.
-
His son Fernando is born.
-
Nuño de Guzmán conquers the Tarascan Empire, giving rise to the Kingdom of Nueva Galicia.
-
Diego García de Moguer travels on an expedition to the Río de la Plata.
-
Fourth war against Francis I of France
-
His daughter Juana is born.
-
The Viceroyalty of Peru is created after the conquest of the Inca Empire by Francisco Pizarro.