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Thomas Jefferson purchases the Louisiana territory along with much more land from France, doubling the size of the U.S and acquiring control of important port cities and rivers.
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Thomas Jefferson signs the embargo act protecting American trade with foreign nations especially Britain and France, but negatively effecting their economy.
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The United States declares war on Britain, resulting in significant battles and the burning of Washington, D.C.
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Congress passes the Missouri Compromise, allowing a balance between free and slave states in the Union.
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Elias Howe invents a sewing machine, revolutionizing textile production and making a profound impact on the clothing and manufacturing industries.
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Pioneers begin the mass migration along the Oregon Trail to the Pacific Northwest, with ideas of manifest destiny in search of new opportunities.
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Confederate forces attack Fort Sumter, marking the start of the Civil War, a conflict over issues including slavery.
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President Abraham Lincoln issues the Emancipation Proclamation, declaring freedom for enslaved people in Confederate territory.
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General Robert E. Lee surrenders to General Ulysses S. Grant at Appomattox, ending the Civil War.
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The First Transcontinental Railroad is completed, connecting the east and west coasts of the United States.