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The Corps of Discovery leaves Camp Wood and begins its journey up the Missouri River "under a gentle breeze."
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The Corps holds the first Independence Day celebration west of the Mississippi River.
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North of present-day Omaha, Nebraska, the Corps holds a council with the Oto and Missouri Indian
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Lewis and Clark hire French-Canadian fur-trader Toussaint Charbonneau and his Shoshone wife, Sacagawea, to act as interpreters on the journey ahead.
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The men record the temperature at 45 degrees below zero, "colder than [they] ever knew it to be in the States."
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One of their boats nearly overturns and Lewis credits Sacagawea with saving their most important possessions.
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November 24, 1805
Having reached the Pacific, the entire expedition—including Sacagawea and Clark's slave, York—take a vote on where to build their winter quarters. They chose the Clatsop Indian side of the Columbia, and the encampment came to be called Fort Clatsop -
March 23, 1806
After a winter of only 12 days without rain, the men present their fort to the Clatsop Indians and set out for home.