Brief History of the Plagues(Epidemics) in the U.S. By Okaytre Period: 1600 to 2018 Brief History of Disease Outbreaks in the U.S. https://www.timetoast.com/timelines/1896967/edit 1633 Smallpox Smallpox, brought from European settlers, wiped out over 70 percent of the Native American population 1833 Chlorea killed 2-6 Americans per day during the outbreak 1906 Typhoid Fever Spread by Mary Mallon in New York 1916 Polio reported 3,145 death from the outbreak