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Samuel Langhorne Clemens is born in Florida, Missouri, the sixth child of John Marshall and Jane Lampton Clemens.
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Samuel Clemens begins a successful two-year apprenticeship to become a licensed river pilot. He learns the lingo of the trade, including "mark twain," a phrase that refers to the river depth at which a boat is safe to navigate. He soon adopts it as his pen name.
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The Civil War breaks out. Trade along the Mississippi River is halted, forcing an end to Twain's steamboat career. Twain spends two weeks training in a volunteer Confederate militia before it disbands.
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In an adventure later chronicled in the book Roughing It, Twain travels to Nevada with his brother Orion, who had been named the secretary to the territorial governor. He tries his hand at mining and other schemes before becoming a reporter for the Virginia City (Nev.) Daily Territorial Enterprise.
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The short story "Jim Smiley and His Jumping Frog" (later "The Celebrated Jumping Frog of Calavaras County") appears in the New York Saturday Press. The story proves extremely popular and raises Twain's profile as a writer.
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Twain travels to Hawaii as a reporter for San Francisco's Alta California newspaper. When he returns to the mainland a few months later, he gives his first public lecture. It's a hit.
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Mark Twain's first book, The Innocents Abroad, becomes a bestseller.
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In the span of less than a year, Twain publishes both his greatest fiction and non-fiction works: The Adventures of Huckleberry Finn, and a biography of President Ulysses S.
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Pudd'nhead Wilson, Twain's last novel, is published. After ten difficult years, Twain's publishing house, Charles L. Webster & Co., finally goes belly-up. The writer finds himself essentially bankrupt. Close friend Henry Huttleston Rogers takes over his finances, saving him from complete disaster.
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Twain's wife Livy dies after a serious two-year illness. Following his wife's death, Twain moves to New York City and begins writing his autobiography.
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Mark Twain died on April 21,1910