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Christopher Columbus is born in 1451 on October 31, In Genoa Italy
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One of the major publications of Renaissance natural philosophy, the Epitome of Ptolemy's Almagest appears; the authors, Georg Peurbach and Johannes Regiomontanus, symbolize a shift from reverence for Ptolemy and antiquity to respect coupled with confident innovation
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Georg Peurbach's New Theory of the Planets was published.
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Gabriele Falloppio announces his discovery of the fallopian tubes in his Anatomical Observations.
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Galileo Galilei is born in Pisa, Italy
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Tycho Brahe, having been ousted from Uraniborg by the King of Denmark, moves to Benateky, outside Prague, under the patronage of Rudolph II, Emperor of the Holy Roman Empire.
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1601 -- Thomas Harriot proposed the sine law of refraction, which he failed to publish
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Galileo publishes his strategic essay, The Assayer where he argues against Aristotle and the Scholastics in favor of mathematical and experimental methods, moving deftly across many topics, from statics and dynamics to his theory of matter.
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Publication of the first Latin edition of Newton's Opticks with its Queries
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Newton's Observations Upon the Prophecies is published; some eleven printings follow
