-
#1
Initial contact of an allergen is made. -
#2
Large amounts of an allergen specific IgE Antibodies are made. -
#3
The IgE molecules set out to find histamine-producting mast cells -
#4
The IgE molecules attach to mast cells ('priming' them). -
#5
Upon re-exposure to an allergen, the IgE primed mast cells releases large amounts of histamine and other inflammatory chemicals -
#6
The chemicals released cause an allergic reaction.
