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President Franklin losses his son due to smallpox.
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John Adams (1735-1826) underwent variolation during a Boston epidemic.
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Catherine the Great of Russia was inoculated by physician Thomas Dimsdale.
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Benjamin Jesty was a farmer and cattle breeder, inoculated his wife and two sons with matter from a cowpox lesion on one of his cows.
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Andrew Jackson future U.S. president, contracted smallpox at age 14 while being held prisoner by the British.
