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Juan Luis Vives in his On the Disciplines argues for the reform of education and a more receptive approach to skills traditionally associated with the craft and trade traditions.
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Georg Joachim Rheticus, a friend of Copernicus and the presumed author, provides an account of the heliocentric hypothesis in his Narratio prima (First Account).
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In mathematics, Girolamo Cardano's The Great Art contained many algebraic innovations and new methods for treating equations of the third degree.
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A noted Renaissance anatomist, Realdo Colombo's De re anatomica (On Anatomy) treats pulmonary circulation of the blood, and like Vesalius, argues against a number of conclusions put forward by the ancient anatomist, Galen
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Gabriele Falloppio announces his discovery of the fallopian tubes in his Anatomical Observations.
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Galileo Galilei born at Pisa, Italy, February 16
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Michelangelo Buonarroti dies at Florence, 18 February
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William Shakespeare born in England, 23 April
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Pope Gregory XIII suggested reform of the Julian calendar, thus leading much of Catholic Europe away from the Julian calendar to the Gregorian
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In mathematics, Simon Stevin proposes the use of decimals.
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Tycho Brahe dies at his castle new Prague.
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Thomas Harriot proposed the sine law of refraction, which he failed to publish.
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Galileo Galilei demonstrates that a projectile follows a parabolic path.