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Samuel Langhorne Clemens, known as Mark Twain, is born in Florida, Missouri.
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Clemens began a two-year apprenticeship to become a licensed river pilot. He also adopted his pen name "Mark Twain" from a pilot lingo.
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Civil War breaks out, halting river trade. Twain serves two weeks with Confederate irregulars, then moves to Nevada with his brother.
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Twain's first short story "The Celebrated Jumping Frog of Calavaras County" is published. The story became popular and Twain's profile as a writer is raised.
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Twain's first book, "The Innocents Abroad", becomes a best seller.
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Twain marries Olivia Langdon, who becomes an important editor of his work. Their son is born later that year.
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Mark Twain publishes his famous book The Adventure of Huckleberry Finn.
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Mark Twain dies at the age of 74 at his home in Redding, Connecticut.