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Isabella was born in the town of Madrigal de las Altas Torres. Daughter of John II, King of Castille and Isabella of Portugal.
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John II, the father of Isabella I, dies and is succeded to the throne by Henry IV, the half-brother of Isabella.
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A battle at Olmedo in Castile involving the belief that Alfonso, Isabella's full brother, had the right to the throne.
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Alfonso, the brother of Isabella dies when the people wanted him to be king and suspicions arise that Henry IV might have poisoned him to ensure his position as king. He died at the age of 14.
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Isabella and Ferdinand marry in the Palacio de los Vivero in Valladolid
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Isabella and Ferdinand recieve the keys of Granada after the last sultan of Granada, Muhammad XII, surrendered. A treaty was signed to give the Moors religious tolerance and fair treatment for their surrender. This ends the spanish Reconquista.
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Isabella and Ferdinand issued an edict that ordered to expel all Jews from Castile and Aragon.
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Christopher Columbus departs to sail off to the Indies for an expediton. The event is sponsored by Isabella and Ferdinand.
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Queen Isabella dies in the castle "La Mota" in Medina del Campo at age 53