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When Edgar was a baby his father abandoned his family.
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His mother died of Tuberculosis at 23 when he was still a young child.
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His first love died when they were only 15 because of brain cancer.
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Edgar goes into 2,000 dollars in debt after gambling. He asks his foster father for help but he refuses.
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Edgars foster mother dies of tuberculosis.
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Edgers older brother Henry dies of Tuberculosis
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His wife Virginia starts bleeding from the mouth while singing for Poe and her mother.
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Edgar's wife finally dies after years of suffering of Tuberculosis
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Poe calls of the wedding because his brides mother didnt wont him to have any rights to her daughters money which Poe took as an insult.