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Dutch scientist Antoine van Leeuwenhoek designed high-powered single lens microscopes in the 1670s.
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They lack a sophisticated digestive system. So as they move through a corpse or rotten food, they secrete fluid containing digestive enzymes to help them dissolve their foul meal.
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Micrographia is a historically significant book by Robert Hooke about his observations through various lenses.
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The abbot Felice Fontana sighted the nucleus in epithelial cells in the year 1781; however this structure had probably been viewed in animal and plant cells in the first decades of the 18th century.
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(1830s) That technical problem was not solved until the invention of achromatic lenses, which were introduced about 1830.
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It contains beautiful descriptions and drawings of nerve cells studied by using histological methods and microdissections made with thin needles under the microscope
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It was the development of the microtome technique and the use of new fixing methods and dyes greatly improved microscopy.
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When Golgi developed the ‘black reaction’22, which he announced to a friend with these few words, “I am delighted that I have found a new reaction to demonstrate, even to the blind, the structure of the interstitial stroma of the cerebral cortex. I let the silver nitrate react with pieces of brain hardened in potassium dichromate. I have obtained magnificent results and hope to do even better in the future.”
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Wilhelm His sought some unification in neurology by proposing that the nerve cell body and its prolongations form an independent cellular unit.
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This term was introduced by C. Gamier for highly developed endoplasmic reticulum with ribosomes in synthetically active cells. Thus, ergastoplasm refers to well-developed endoplasmic reticulum along with ribosomes in some parts of metabolically active cells.