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born in Pella, Macedonia
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- Alexander serves as regent and puts down a revolt of the Maedi.
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Alexander helps his father win the Battle of Chaeronea.
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Alexander becomes ruler of Macedonia.
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Wins Battle of the Granicus River against Darius III of Persia.
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Wins Battle of Issus against Darius
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Wins siege of Tyre; attacks Gaza, which falls.
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Founds Alexandria. Wins Battle of Gaugamela (Arbela) against Darius
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Kills Black Cleitus for an insult at Samarkand
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June 10 - Dies at Babylon in the palace of Nebuchadnezzar II