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Before Dr. Manette is imprisoned he meets the Evremonde brothers. One of the brothers has raped a woman and killed her husband, brother, and, indirectly, her father. Manette is imprisoned when the brothers find out that he is trying to tell the minister about what they've done. While in prison, Manette takes up shoe making.
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Since Lucie's father, Alexander Manette, has disappeared Lucie is assumed an orphan and taken by Mr. Jarvis Lorry of Tellson's and Co. to London.
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Jarvis Lorry and Lucie Manette meet up and go to Paris. Lucie finds out that her father is not dead and is, in fact living in a wine shop. Dr. Manette has been rescued from prison and has been taken care of by Earnest Defarge and his wife. Manette can only identify himself as the number of his prison cell: 105 North Tower.
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Charles Darney is tried for treason in the Old Bailey in London. Lucie, Dr. Manette, and Mr. Lorry are all witnesses. Darney is saved when Sydney Carton points out their resemblance, proving that no positive identification can be established.
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Charles Darney visits his uncle, the Marquis Evrémonde in France. Darney denounces his inheritance that night. In the morning, the Marquis is found murdered.
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On the day of their wedding, Darney tells Dr. Manette his true last name and Manette has a mental relapse.
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Jerry Cruncher witnesses a funeral for Roger Cly (a spy and witness against Charles Darney in the case in 1780). Cruncher later goes on to dig up Cly's grave but finds it empty.
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John Barsad was also a witness against Charles Darney in the case in 1780.
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The storming of the Bastille also signals the start of the French Revolution.
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When he arrives in Paris, Darney is arrested for being an emmigrant and an arristocrat.
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Mr. Lorry is going to Paris to take care of the property in the Paris branch of Tellson and Co.. Darney has recieved a letter from his faithful servant Gabelle asking Darney to come back to Paris and save him. This is what causes Darney's secret return to France. Darney is not aware of all of the danger he may be in.
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The Manettes arrive around the time of the September massacres. Dr. Manette uses his influence to protect Darney.
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When Darnye is first tried, Dr. Manette uses his influence to have Darney freed. Darney is then released and allowed to go home. Darney is reaccused by the Defarges and is taken prisoner again. When Darney is retried, he is found guilty and sentanced to death.
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In order to keep Lucie happy, Sydney Carton takes Darney's place at the guillotine and is killed instead.