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emperor constantine established Constantinople as the new capital of the Roman empire. this location helped the city become a major center of trade and it marked the beginning of the byzantine empire
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Justinian l ruled the byzantine empire and sought to revive the empires greatness. he commissioned the construction of hagia Sophia and codified Roman laws.
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The Byzantines retake north africa from the vandals. this is while they are under Belisarius and this ends up ending the vandal kingdom. and the revival of north Africa is completed.
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Muhammad's migration from mecca to medina marked the beginning of the Islamic calendar. this event led to the spread of Islam.