Spread of the Black Death By 26GE102640 1320 Gobi Desert 1338 Lake Issyk Kul 1345 Lower Volga River 1346 Crimea and Caucasus 1347 Messina, Sicily, Constantinople, Alexandria, Egypt, Italy, Greece 1348 Genoa, Venice, Britain, Ireland 1349 Northern Europe, Mecca 1351 Yemen 1353 Moscow