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16th century China, first variolation
Nasal insufflation
https://school.eb.com/levels/middle/article/variolation/74854 -
1721, variolation popularized in England
infecting yourself with smallpox
https://school.eb.com/levels/middle/article/variolation/74854 -
1721, black man teaches inoculation
In 1721, variola spread to Massachusetts, a black man then taught his master how to survive and spread inoculation
https://www.history.com/articles/smallpox-vaccine-onesimus-slave-cotton-mather -
1796, Edward Jenner first vaccine test
He infected a kid with cowpox, then with smallpox, and he was fine
https://explore.proquest.com/sirsdiscoverer/document/2250427759?searchid=1748460108&accountid=3541 -
1800th century, scarification
new variolation technique
https://school.eb.com/levels/middle/article/variolation/74854 -
1800, vaccine reaches America
In 1800, the smallpox vaccine reached people like Thomas Jefferson for research
https://www.smithsonianmag.com/smart-news/thomas-jefferson-conducted-early-smallpox-vaccine-trials-180954146/ -
1905, vaccination mandatory
A Supreme Court case ruled vaccination mandatory.
https://www.history.com/articles/smallpox-vaccine-supreme-court -
1749, Birth of Edward Jenner
Discovered that catching cowpox prevents smallpox, the father of immunology.
https://explore.proquest.com/sirsdiscoverer/document/2703927128?searchid=1748459410&accountid=3541 -
1967, WHO global vaccination program
The Who tries to stop smallpox
https://school.eb.com/levels/middle/article/smallpox-vaccine/634536 -
1980, Smallpox eradication
Smallpox was eradicated using vaccine
https://school.eb.com/levels/middle/article/smallpox-vaccine/634536