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Safiye Ali was born on February 2, 1894, in Istanbul. Her father was Ali Kırat Pasha and her mother was Emine Hasene Hanım.
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After attending Kaptanpaşa Primary School and Üsküdar American Academy, she went to Germany to study at the Medical Faculty.
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She graduated from the University of Würzburg in Germany, becoming Turkey's first female doctor.
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She returned to Istanbul and began working as a private physician, specializing in women’s and children's diseases.
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She started working at the Ministry of Health and Social Welfare, focusing on women's and children's health.
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She served in the Turkish Red Crescent Society (Hilal-i Ahmer Cemiyeti), continuing her work in women’s and children’s health.
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She began lecturing on gynecology and obstetrics at Istanbul University Medical Faculty, while also continuing to treat patients in her clinic.
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She attended the International Women's Congress in Berlin in 1935, representing Turkey
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After World War II, due to the political atmosphere in Turkey, she returned to Germany and continued her work in Frankfurt.
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Safiye Ali passed away on July 5, 1952, in Dortmund, Germany. She was buried in a Muslim cemetery in accordance with her will