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He was born near the Tuscan town of Vinci. He was the illegitimate son of local lawyer.
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After he was apprenticed to the sculptor and painter Andrea del Verrocchio in Florence, he became an independent master -
He moves to Milan to work for the ruling Sforza family as an engineer, sculptor, painter and architect. -
While in Florence, he painted several potraits, but the only one that survives is the famous "Mona Lisa" (1503-1506) -
He moves to Chateau of Cloux in France after the invitation of the French king Francis I, where he dies.