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Phillip married his cousin Maria of Portugal in 1543 and she died in 1545.
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In 1554 Philip married Mary I of England and became joint sovereign of England until Mary’s death, without issue, in 1558.
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Philip’s third marriage, with Elizabeth of Valois, daughter of Henry II of France, in 1559, was the result of the Peace of Cateau-Cambrésis, which, for a generation, ended the open wars between Spain and France. Elizabeth bore Philip two daughters, Isabella Clara Eugenia (1566–1633) and Catherine Micaela (1567–1597). Elizabeth died in 1568
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There was a Protestant uprising in the Netherlands, in 1567, he sent the Spanish army to put them down.
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In 1570 Philip married Anna of Austria, daughter of his first cousin the emperor Maximilian II. She died in 1580.
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The Spanish Armada led by King Philip II of Spain attempted to invade England in 1588, to avenge the death of Mary Queen of Scots in 1587.
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He was like Philip II, King of Portugal, Naples, Sicily and Sardinia and Duke of Milan from 1598 until his death in 1621.
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Phillip II died