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Philip II is born in Palacio de Pimentel, Valladolid, Spain
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Maria of Portugal, wife of Philip II of Spain, dies in childbirth, when the King's son Don Carlos (1545-1568) was born.
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Philip II, son of Charles V, is crowned King of Spain after Charles V abdicates.
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Henry II of France and Philip II of Spain sign the truce of Vaucelles, calling a halt to this phase of the long-running Habsburg-Valois conflict
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Philip the II begins to tax lower class more because Spain went bankrupt which prevented Spain from developing a middle class.
Spain went bankrupt because there was a growing population and merchants raised prices for food and other products. -
Philip II married Mary I of England which brought Spain and England closer together in 1554, but then she died later to Reproductive system disease in 1558.
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Elisabeth of Valois dies while giving birth to Infanta Catherine Michelle of Spain. Catherine (mother) hoped King Philip II might marry her younger daughter, Elizabeth's sister Margaret of Valois, but Philip was determined to take his French connection no further, even though Elizabeth's death was mourned in Spain.
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Anna of Austria, Queen of Spain gives birth to Philip III of Spain in Madrid, Spain. Philip II's only surviving son.
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King Henry of Portugal died leaving no children. The Duke of Alba invaded Portugal and put it under Spain's rule. Philip II of Spain was proclaimed King of Portugal and united the colonial empires of Spain and Portugal.
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King Philip II of Spain decides to invade England to avenge the country for its execution of Mary Queen of Scots – Spain’s Catholic ally – in 1587. This marked the turning point in years of dispute and religious differences between Catholic Spain and Protestant England. (Spanish Armada)
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Philip II dies to Cancer in El Escorial, Spain
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The Spanish Golden Age was the period of Spanish literature extending from the early 16th century to the late 17th century, generally considered the high point in Spain’s literary history.