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Zacharias Janssen
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Cornelis Drebbel
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Galileo Galilei
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Creado por Galileo Galilei
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Realizado por Giambattista Odierna
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Comienzan a usar el microscopio los naturalistas italianos, holandeses e ingleses
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van Leeuwenhoek reported the discovery of micro-organisms
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In 1893 August Köhler developed a key principle of sample illumination, Köhler illumination, which is central to achieving the theoretical limits of resolution for the light microscope.
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Differential interference contrast illumination by Georges Nomarski in 1955; both of which allow imaging of unstained, transparent samples.