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Joseph Priestley and Antoine Lavoisier discover a new gas named oxygen, discrediting the basic theory of chemistry at the time
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Humphry Davy discovers what's now known as laughing gas. Davy started inhaling it himself to discover the effects.
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Russian chemist Dmitri Mendeleev develops the periodic table
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Marie curie discovers several elements including polonium and radium
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Henry Mosely proves that every element's identity is based on number of protons it has